Plinest is an Italian polynucleotide skin treatment. Polynucleotides are natural repair building blocks, purified from salmon or trout DNA, that are very similar to the ones already found in our own skin, so the body accepts them well.
Rather than adding volume or freezing muscles, Plinest works by helping your skin heal and renew itself from within. It supports collagen production, improves hydration and elasticity, and strengthens the skin so it looks smoother, firmer, and healthier over a course of sessions. Think of it as a repair-and-rejuvenate treatment rather than a cosmetic top-up.
Plinest is injected in small amounts just beneath the surface of the skin, across the area being treated.
Once in the skin, the polynucleotides act like a repair signal, encouraging your skin to regenerate. They help boost collagen, improve elasticity and hydration, and calm the low-grade irritation that can leave skin looking tired and dull. Because it works by genuine repair rather than by adding filler, results appear gradually and look natural.
This makes Plinest a good option for skin that is dull, thinning, or simply worn out, rather than for changing the shape of the face. During your consultation, our doctors will assess your skin and recommend the right approach and number of sessions.
Plinest is known for improving skin quality from the inside out. Its main benefits include:
Everyone’s skin and goals are different, so our doctors will talk you through what you can realistically expect at your consultation.
At Euphie Clinic, Plinest is used to improve skin quality and support renewal:
A quick chat with our doctors will confirm whether Plinest suits your skin, and which approach is right for you.
Plinest comes in more than one form, each suited to different needs. At Euphie Clinic, we carry two:
The original polynucleotide treatment, used to improve overall skin quality. It is the go-to choice for dull, tired, or ageing skin, helping to boost collagen, hydration, and firmness for a healthier, more refreshed look.
A version designed for a quicker, more convenient treatment experience while still delivering the skin-repairing benefits of polynucleotides. It is a good option if you want Plinest’s rejuvenating effects with a more streamlined session.
At Euphie Clinic, our doctors will assess your skin during the consultation and decide which Plinest option, or combination, will give you the best result.
Knowing what to expect can help you feel at ease. Here is what a typical visit looks like:
Results with Plinest depend as much on the doctor as on the product: reading your skin correctly, injecting evenly at the right depth, and planning the course of sessions your skin needs to repair and renew properly.
Every Plinest treatment at Euphie Clinic is performed by a medical doctor who is LCP-certified, the credential required in Malaysia to carry out aesthetic procedures such as injectables. Our doctors hold recognised medical degrees (MBBS) with extra training in aesthetic medicine, and all follow the same treatment protocols, so you receive a consistent standard of care whichever doctor you see.
The cost of Plinest in Malaysia depends on which option is used, how many sessions you need, and the area being treated. Since every skin is different, we always tailor the plan to you rather than selling a fixed package. For pricing based on your own plan, please contact us or visit Euphie Clinic for a consultation.
When choosing where to have your treatment, it comes down to who performs it, the expertise behind it, and the level of care. Here is what we offer:
Doctor-Led, Always
Backed By 20+ Years of Aesthetic Heritage
A Treatment Plan Built Around You
Plinest polynucleotide treatment is available at all Euphie Clinic locations:
| Clinic | Address | Phone |
|---|---|---|
| Euphie Clinic, Damansara Heights | A-2-03, Level 2, 5th Place, The FIVE, Kompleks Pejabat Damansara, No. 49, Jalan Dungun, Bukit Damansara, 50490 Kuala Lumpur | +603-2011 2558 +6012-8679 148 |
| Euphie Clinic, Damansara Uptown | 40-G, Jalan SS 21/35, Damansara Utama, 47400 Petaling Jaya, Selangor | +603-8679 3581 +6012-8679 940 |
Book a consultation with our doctors at Euphie Clinic. We will look at your skin, talk through your goals, and tell you whether Plinest is the right fit, which option suits you, and what it will cost. If something else would suit you better, we will tell you that too.
Most patients find it very manageable. A numbing cream is applied to the treatment area before the injections begin to minimise discomfort. The blood draw from the arm feels the same as a standard blood test. Overall, most patients rate the experience as mild discomfort.
For skin rejuvenation, some patients notice a subtle improvement in radiance within the first week. More visible improvements in texture, fine lines, and scar appearance typically become noticeable around 4 to 6 weeks after the session. For hair loss, visible improvement in thickness and density is generally seen at around 3 to 6 months after beginning the treatment course.
Yes. Because PRP is made entirely from your own blood, the risk of an allergic reaction or rejection is extremely low. It is considered one of the safest injectable treatments available. The equipment used to prepare the PRP is sterile and single use. PRP should always be performed by trained medical professionals in a licensed clinic.
Yes, and combination approaches often produce the strongest results. For skin, PRP pairs well with Pico Majesty Laser, Sylfirm X, and skinboosters. For hair loss, it works particularly well alongside Fotona Hair Restore Laser and topical treatments such as Minoxidil. Your doctor will advise the safest and most effective combination for your specific goals.
PRP is not recommended for individuals who are pregnant, have blood disorders or severe anaemia, have active infections or skin conditions in the treatment area, have certain autoimmune conditions, or are on immunosuppressant medications. A thorough consultation with our doctors at Euphie will confirm your suitability before any treatment begins.
For skin rejuvenation, results typically last several months with maintenance. For hair loss, results depend on the individual and whether the underlying cause of thinning continues to progress. PRP does not permanently stop hair loss, so regular maintenance sessions are needed to sustain improvements over the longer term. Your doctor will advise the most appropriate maintenance schedule for your situation.
Beyond aesthetics and hair loss, PRP is an active area of research across several medical fields. In orthopaedics, it is being studied as a treatment for joint pain, tendon injuries, and osteoarthritis, with the goal of using concentrated growth factors to support tissue repair and reduce inflammation without surgery. In female reproductive medicine, researchers are investigating PRP’s potential to support uterine lining health and improve outcomes in certain fertility treatments. It is also being explored in the context of erectile dysfunction, where improved blood vessel formation and tissue repair may support better function. In wound care, particularly for diabetic foot ulcers, PRP has shown promising results in accelerating healing in tissue that is otherwise slow to repair due to poor circulation and a compromised immune response. While these applications are still under active research and are not yet standard practice across all medical settings, they speak to the broader potential of the body’s own regenerative biology when concentrated and applied with precision.
