Linerase

Linerase is a collagen-based injectable treatment that stimulates the skin's natural collagen production to improve skin quality, firmness, and structural support over time. Developed in Italy, it uses highly purified Type I Collagen to help rebuild the skin's foundation from within, making it suitable for concerns such as skin ageing, acne scars, wrinkles, and skin laxity. Unlike fillers, Linerase does not add volume or alter facial contours, instead delivering gradual and natural-looking improvements through collagen regeneration.

Sessions Required
3 sessions and above
Duration of Results
Long-lasting with maintenance sessions
Session Duration
30–60 mins
Downtime
Mild redness, swelling, or injection marks for 1–3 days
Skin Concerns
Fine Lines & Wrinkles Loss of Skin Firmness Scars Stretch marks Thin skin Uneven skin texture
Fine Lines & Wrinkles
Loss of Skin Firmness
Scars
Stretch marks
Thin skin
Uneven skin texture

What is Linerase?

Linerase is an advanced collagen-based injectable treatment developed in Italy for aesthetic use. At Euphie, it is offered as a regenerative treatment for patients who want genuine, long-term skin improvement without adding volume or changing how their face looks. 

The active ingredient in Linerase is a highly purified form of Type I Collagen, the same type of collagen that forms the structural foundation of young, firm skin. As we age, our bodies produce less of this collagen naturally, which leads to skin that becomes thinner, less firm, and more prone to fine lines and sagging.

How Does Linerase Work?

Once injected into the skin, Linerase works in two ways at the same time:

  • It provides immediate structural support. The purified collagen in Linerase integrates into the skin tissue and creates a scaffold that supports the surrounding area right away, giving the skin a better structural environment to work with.
  • It activates your skin’s own collagen production. The presence of Linerase in the skin signals the collagen-producing cells to become more active and produce new collagen fibres of their own. It also encourages new collagen-producing cells to form, which means the skin continues to improve even after the Linerase itself has been absorbed.

On top of this, Linerase supports the formation of new tiny blood vessels in the treated area, improving the delivery of oxygen and nutrients to the skin tissue. It also has calming properties that make it suitable for sensitive or post-treatment skin.

Because results come from your skin’s own collagen production, they develop gradually and look entirely natural. Most patients start to notice visible improvement within 2 to 3 weeks of their first session, with continued enhancement over the following months.

Key Benefits of Linerase

  • Works well with other treatments: Pairs effectively with lasers, Sylfirm X, skinboosters, and HIFU for enhanced results.
  • Stimulates real collagen production: Your skin produces its own new collagen rather than just being filled or masked.
  • Natural-looking results: Improvement develops gradually from within with no risk of looking overdone or artificial.
  • Long-lasting: Results from a full course of treatment can last several months as collagen continues to rebuild.
  • CE certified and MOH registered: Clinically proven with a strong safety record since 2015 and no reported serious side effects.
  • Treats multiple concerns: Fine lines, acne scars, skin laxity, and thinning skin all in one treatment.
  • Suitable for delicate areas: Because it does not add volume, it works well in thin or fragile skin zones where fillers are not ideal.
  • Mild downtime: Non-surgical with only temporary redness or mild swelling at the injection sites.

What Skin Concerns Can Linerase Treat at Euphie?

  • Skin Rejuvenation and Anti-Ageing
    For patients who are starting to notice their skin looking less firm, more dull, or generally more tired with age, Linerase offers a way to restore skin quality from the inside out. By rebuilding the skin’s collagen network gradually, it improves skin density, firmness, and resilience over a course of sessions. Most patients describe the result as looking refreshed and healthier, rather than looking like they have had a treatment. Because the improvement is driven by the skin’s own collagen, the outcome is subtle, natural, and progressive.
  • Acne Scars
    Acne scars form when the inflammation from a breakout damages the collagen structure beneath the skin, leaving behind dips or textured marks. Linerase helps by delivering collagen directly to the scarred tissue, stimulating the area to regenerate and gradually fill in from below. Over a course of sessions, the depth and texture of the scars progressively improve as new collagen forms in the damaged areas. Many patients notice a visible difference in scar appearance after 2 to 3 sessions, with continued improvement over the following months.
  • Wrinkles and Fine Lines
    Unlike botulinum toxin, which works by relaxing the muscles that contribute to expression lines, and fillers, which restore volume beneath the skin, Linerase works by stimulating collagen regeneration within the skin tissue. It rebuilds the collagen in the skin tissue beneath the wrinkle, allowing the skin to smooth out naturally from within as new structural support forms. It is particularly effective for fine to moderate lines in areas where the main cause is skin thinning and collagen loss rather than muscle movement.
  • Skin Laxity and Thinning Skin
    One of Linerase’s most valued uses is for skin that has become noticeably thinner, looser, or crepey with age. This is especially common in the lower face, jawline, neck, chest, and hands, areas that do not always respond well to volume-based fillers. Because Linerase rebuilds the structural foundation of the skin rather than adding bulk, it produces a tightening and firming effect that is well suited to these concerns without changing the shape or look of the treated area.

Frequently Asked Questions

Is Linerase the same as a dermal filler?

No. They work in completely different ways. Fillers physically fill a space in the tissue with a gel that creates volume. Linerase stimulates your own skin to produce new collagen over time. It does not add bulk or change your facial contours in a dramatic way. The improvement comes entirely from your skin’s own natural regenerative response.

Yes. Linerase is CE certified, registered with Malaysia’s MOH, and has been used in aesthetic medicine since 2015 with no reported serious side effects. The purified collagen it contains has a very low risk of causing an allergic reaction. Patients with known allergies to collagen should let their doctor know during the consultation.

Most patients notice an initial improvement in skin quality and glow within 2 to 3 weeks of their first session. More visible improvements in firmness, texture, and scar appearance develop progressively over 4 to 8 weeks as new collagen continues to form beneath the surface. The best results are typically seen after completing the full recommended course of sessions.

Yes. Linerase pairs well with laser treatments like Pico Majesty or Fotona Laser for patients working on scars and skin texture, with Sylfirm X for a more comprehensive skin improvement approach, and with skinboosters for patients who want both collagen stimulation and deep hydration at the same time. Your doctor will advise the most appropriate combination and timing for your goals.

Linerase is not recommended for individuals who are pregnant, have an active skin infection or inflammation in the treatment area or have a known allergy to collagen injection. A thorough consultation with our doctors at Euphie will confirm your suitability before any treatment begins.

Results from a full course of Linerase build progressively over several months as new collagen continues to form and support the skin’s structure. It is one of the longer-lasting non-surgical rejuvenation treatments available. Regular maintenance sessions help sustain and build on these results over time.