Profhilo is a family of injectable bio-remodelling treatments developed in Switzerland using their patented NAHYCO Hybrid Technology. Unlike traditional fillers that add volume, or skinboosters that primarily hydrate, Profhilo works at a biological level to stimulate the skin’s own repair and renewal process from within.
At Euphie, we offer two formulations under the Profhilo range, each working at a different depth and addressing a different layer of ageing:
Profhilo is injected into the dermis, the middle layer of the skin. It is designed to improve skin quality itself — addressing dullness, dehydration, fine lines, crepiness, and mild laxity by triggering the skin’s own collagen and elastin production.
Profhilo Structura is injected into the deeper layer beneath the skin for patients experiencing more advanced structural ageing — hollow cheeks, jowling, sagging, and jawline descent — by regenerating and repositioning the facial structure from beneath.
Both use the same ultra-pure hyaluronic acid technology with no chemical cross-linking agents, making them among the most biocompatible injectables available today.
When injected, Profhilo’s high concentration of hyaluronic acid immediately begins drawing and holding moisture in the skin. Think of it as deep, structural rehydration — not just on the surface, but within the tissue itself.
Over the following weeks, as the product integrates into the skin, it sends signals to the cells responsible for making collagen and elastin, prompting them to become more active again. The result is skin that progressively becomes firmer, more elastic, and more resilient, with improved texture and a natural, healthy glow.
The treatment uses the BAP (Bio Aesthetic Points) technique — only 5 precise injection points on each side of the face. From these points, the product spreads evenly beneath the skin, providing full and uniform coverage without the need for dozens of injection marks.
General Protocol: 2-3 sessions, spaced 4 weeks apart. Maintenance sessions every 6 to 9 months.
Profhilo Structura works in the deeper fat layer beneath the skin, which is the structural foundation of the face. As we age, these fat compartments shrink and descend, causing the face to look flatter, hollower, and less defined.
Structura is delivered using a cannula (a blunt-tipped flexible instrument rather than a sharp needle) into targeted points beneath the skin. Once in place, it works to restore and reposition this deeper facial structure from within, creating a natural lifting and contouring effect in the cheeks, midface, and jawline over time. It also triggers collagen and elastin production in the surrounding tissue, improving firmness in the area as well.
In plain terms, Profhilo treats the skin. Profhilo Structura treats the structure beneath the skin. Used together, they address both layers of ageing comprehensively.
General Protocol: 2 sessions, spaced 4 to 6 weeks apart. Maintenance every 6 to 9 months.
Profhilo is widely known as a skin remodelling treatment used for overall skin rejuvenation and early signs of ageing. As the skin naturally loses collagen, elastin, and hyaluronic acid over time, it may become less firm, less elastic, and appear dull or creased. Profhilo works by delivering a high concentration of hyaluronic acid that spreads within the skin and helps improve hydration and support tissue quality. After a treatment course, patients may notice improvements in skin hydration, elasticity, texture, and a more radiant appearance, with gradual softening of fine lines over time.
Profhilo is particularly effective for skin that has become loose, thin, or crepey due to ageing. Because it stimulates elastin production alongside collagen, it has a genuine firming effect that goes beyond what conventional hydrating skinboosters can achieve. It works well for crepey skin on the lower face, jawline, neck, and decolletage.
While Profhilo does not treat rosacea directly, it supports skin healing and strengthens the skin barrier, making it a suitable option for individuals with redness-prone or sensitive skin. By stimulating collagen and elastin and restoring deep hydration, it helps the skin become more tolerant and less reactive over time. Its ultra-pure formulation, free of chemical cross-linking agents, makes it exceptionally gentle and well-tolerated even by the most reactive skin types.
As the fat compartments in the midface diminish with age, the cheeks flatten, the area under the cheekbones becomes hollow, and the face loses its youthful projection. Profhilo Structura restores this by working within the deep structural layer, bringing back the subtle fullness that gives the face a lifted, refreshed appearance without an overdone look.
When the structural support in the upper and midface reduces and descends, it contributes to heaviness and sagging along the jawline and jowl area. By restoring and repositioning this structure upward, Profhilo Structura helps reduce the appearance of jowls and restores a more defined, lifted lower face profile.
Age-related changes cause the face to lose the angles and contours that define a youthful facial shape, including the cheeks, lateral face, and zygomatic region. Profhilo Structura restores structural support in these areas, improving overall facial proportions naturally.
As facial support descends, the overlying skin loses its foundation and begins to crease and sag. Profhilo Structura addresses this at the source while also stimulating collagen and elastin production in the surrounding tissue to improve skin firmness and texture from below.
Profhilo is injected into the skin itself and works to improve skin quality — hydration, elasticity, firmness, and fine lines. It is ideal for patients with dullness, dehydration, and early to moderate signs of ageing. Profhilo Structura is injected into the deeper structural layer beneath the skin and works to restore facial lift, midface projection, and contour. It is suited for patients with more advanced structural ageing such as hollow cheeks, sagging, and jawline descent. Both can be used together for a comprehensive result.
Yes, and combining both is actually one of the most comprehensive approaches to facial rejuvenation available without surgery. Profhilo addresses the skin quality layer while Profhilo Structura restores the structural foundation beneath it. Your doctor at Euphie will advise whether doing both in the same session or staggering the sessions makes more sense for your specific concerns.
No. Dermal fillers are thicker gels that add volume and reshape specific features. Profhilo is a thin, spreadable hyaluronic acid complex that flows evenly beneath the skin to improve tissue quality without adding volume or changing your facial structure. Profhilo Structura similarly does not add bulk. It restores the face’s own structural integrity through regeneration rather than filling.
They are related but not the same. Both use hyaluronic acid and improve hydration, but Profhilo goes further by stimulating collagen and elastin through its bio-remodelling effect. Profhilo also contains a significantly higher concentration of HA than standard skinboosters, and its unique formulation allows it to spread evenly and integrate into the tissue in a way that typical skinboosters do not.
Profhilo’s reputation for being uncomfortable, even with just 5 injection points, is something we hear from patients who have tried it at other clinics. The reality is that the BAP points are placed in areas that can be quite sensitive, and numbing cream alone is not always sufficient.
Â
At Euphie, we take a different approach. We use a combination of topical numbing cream and numbing medication so that the majority of our patients genuinely do not feel significant pain during the session. Patient comfort is not an afterthought here — it is built into how we do the treatment.
For Profhilo, most patients notice improved skin hydration and a subtle glow within the first 1 to 2 weeks. More significant improvements in firmness and fine lines become visible 4 to 8 weeks after the second session. For Profhilo Structura, visible lifting and contouring improvements are typically noticed within 4 to 6 weeks of the first session, with optimal results after the second session.
Yes. Profhilo pairs well with Sylfirm X for patients wanting both structural skin improvement and targeted concern treatment, or with Pico Majesty Laser for patients managing pigmentation alongside skin laxity. Both Profhilo and Profhilo Structura can be combined with botulinum toxin, dermal fillers, or HIFU as part of a broader treatment plan. Your doctor will advise the safest combination and timing for your goals.
Both treatments are not recommended for individuals who are pregnant, have active skin infections, or have a history of severe allergic reactions to the product. A thorough consultation with our doctors at Euphie will confirm your suitability before treatment begins.
Results from both Profhilo and Profhilo Structura typically last 6 to 9 months. Regular maintenance sessions help sustain the improvements in skin quality, firmness, lift, and radiance achieved through treatment.
