PDRN – Plinest / Rejuran Healer

PDRN (Polydeoxyribonucleotide) treatments like Plinest and Rejuran Healer are skin-repairing injectables designed to improve overall skin health, texture, and elasticity. These treatments use DNA fragments derived from fish sources. They have been clinically shown to stimulate skin regeneration, reduce inflammation, and repair damaged tissue, making them ideal for natural, long-term rejuvenation.

Sessions Required
3 sessions and above
Duration of Results
4–6 months
Session Duration
30–45 mins
Downtime
Minimal downtime
Skin Concerns
Dull tired-looking skin Fine lines and early signs of ageing Post-acne or post-laser healing Thin crepey skin or skin laxity Weakened or damaged skin barrier
Dull tired-looking skin
Fine lines and early signs of ageing
Post-acne or post-laser healing
Thin crepey skin or skin laxity
Weakened or damaged skin barrier

About This Treatment

PDRN is a naturally occurring molecule that helps regenerate skin at a cellular level. It activates healing and repair processes by stimulating fibroblast activity, collagen production, and tissue regeneration. Rejuran Healer and Plinest are two clinically established PDRN-based treatments widely used across Asia and Europe for anti-ageing and dermal repair.

Plinest and Rejuran Healer are both skin-repair treatments formulated with highly purified PDRN and polynucleotides. Plinest is backed by Italian biotechnology, while Rejuran originates from South Korea. Both aim to improve skin elasticity, hydration, and support skin repair, especially after damage or inflammation.

How Does It Work?

  • Delivers PDRN molecules into the dermis to repair and regenerate skin cells

  • Stimulates collagen and elastin synthesis for improved elasticity and firmness

  • Enhances microcirculation and skin hydration

  • Repairs damaged skin barrier and reduces inflammation

Key Benefits

  • Regenerates Skin from Within
    Activates natural skin healing and boosts collagen at the cellular level

  • Restores Skin Texture and Resilience
    Improves fine lines, roughness, and elasticity for firmer, smoother skin

  • Strengthens the Skin Barrier
    Ideal for sensitive or compromised skin after acne, laser, or stress

Frequently Asked Questions

What is PDRN and how is it used in Plinest or Rejuran?

PDRN (Polydeoxyribonucleotide) is a DNA-derived molecule extracted from salmon that promotes skin repair and regeneration. Plinest and Rejuran use purified PDRN to rejuvenate the skin through microinjections.

HA hydrates and adds volume. PDRN, on the other hand, focuses on repairing and regenerating skin tissue for long-term improvement in texture, elasticity, and barrier strength.

Yes. PDRN has anti-inflammatory properties and helps restore the skin barrier, making it suitable for post-acne care, laser recovery, and sensitive skin types.

Yes. PDRN treatments are often paired with laser therapy, microneedling, or Skinboosters to enhance healing and improve overall outcomes.

Avoid makeup, harsh skincare, and sun exposure for 24–48 hours. Gentle cleansers, moisturisers, and daily sun protection are recommended.