Tired, dull, or ageing skin often reflects damage happening beneath the surface. This is why injectable skin repair treatments have become increasingly popular. At Euphie Clinic, two commonly requested options are Rejuran and Plinest.
Both Rejuran and Plinest are polynucleotide based injectables derived from fish DNA. These polynucleotides support skin repair, hydration, and regeneration by working within the skin rather than adding volume. While they share a similar foundation, the way they are refined and how they perform in the skin differs, making each suitable for different skin needs.
Over time, sun exposure, pollution, stress, and ageing weaken the skin’s ability to repair itself. Polynucleotide treatments help restore this function by supporting cell repair, improving hydration, and strengthening the skin barrier. This leads to smoother texture, healthier looking skin, and improved elasticity over time.
Daily exposure to the sun, pollution, and stress can weaken the skin over time. Treatments like Rejuran and Plinest work beneath the surface to restore hydration, strengthen the skin barrier, and support natural skin recovery. This helps skin look smoother, healthier, and more radiant over time.
Rejuran helps the skin repair itself from the inside, improving texture and radiance gradually. Perfect for anyone dealing with:
Rejuran smooths fine lines, enhances overall skin quality, and restores a youthful glow without adding volume.
Plinest focuses on replenishing moisture and strengthening the skin barrier, helping skin retain hydration and improve elasticity. Recommended for those experiencing:
Plinest keeps skin refreshed, resilient, and comfortable while supporting overall skin wellness.
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Knowing the differences between Rejuran and Plinest can help you choose the treatment that best suits your skin.
| Feature | Rejuran | Plinest |
| Origin | South Korea | Italy |
| Polynucleotide Source | Salmon-derived polynucleotides | Trout-derived polynucleotides |
| Main Focus | Skin repair with emphasis on acne scars, texture damage, and collagen recovery | Skin hydration, barrier strengthening, and long-term skin support |
| Best For | Depressed acne scars, uneven texture, and skin damaged by inflammation or ageing | Dry, sensitive, stressed skin or ongoing skin maintenance |
| Adds Volume? | No | No |
Both treatments improve skin texture, hydration, and overall health without altering facial shape.
While the demand for both treatments continues to grow, knowing their specific uses helps practitioners prevent misuse and ensure good patient outcomes.
Plinest focuses primarily on increasing hydration, increasing elasticity, and improving overall skin quality. Clinicians often use it on the face, neck, and décolleté—areas that respond well to collagen and elastin support. It delivers results gradually, giving the skin a naturally rejuvenated appearance.
Rejuran works more intensively on skin repair and regeneration. Practitioners prefer it to address acne scars, enlarged pores, and weakened skin barriers. It is typically applied to the face and neck, especially when deep healing and restoration are needed.
Each treatment brings its own benefits, and identifying their key roles helps clinicians choose the most appropriate method and effectively customize treatment.
All sessions are performed by LCP certified doctors to ensure safety and results. A typical session includes:
Mild redness or tiny bumps may appear but usually fade within 1-2 days.
Deciding which treatment is right involves looking at the following aspects:
Rejuran is commonly chosen for skin with depressed acne scars, uneven texture, and visible damage caused by inflammation or collagen loss. Plinest is ideal for hydration, sensitive skin, and long-term skin maintenance. Your doctor can create a personalised treatment plan.
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No. These treatments do not add volume. They focus on repairing, hydrating, and rejuvenating the skin.
Most clients start with 2-4 sessions, spaced a few weeks apart. Maintenance sessions help sustain results.
Mild redness or small bumps may appear but typically fade within 1-2 days.
Pregnant or breastfeeding individuals, or those with active infections or certain medical conditions should avoid these treatments. Doctor consultation is required.
Results appear gradually and are not permanent. Regular sessions help maintain skin repair, hydration, and glow.
Receive personalised guidance from our professional doctors to choose the treatment that suits your skin. Improve hydration, repair damaged skin, and enhance your natural glow. Book your consultation today via Contact Us.
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